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Maria René Sendoya Alvarez
Daniel Saavedra Rodriguez
Rommer Alex Ortega Martinez

El Síndrome de Takotsubo (STT), o síndrome del corazón roto, es una miocardiopatía transitoria inducida por estrés, descrita en Japón en los años 90. Se presenta con síntomas que imitan un infarto agudo de miocardio (IAM) y elevación del segmento ST, pero sin la presencia de enfermedad coronaria obstructiva. Presentación del caso: Se trata de una mujer de 84 años que, tras una cirugía ortopédica, sufrió bradicardia severa, alteración de la conciencia y cambios electrocardiográficos sugerentes de IAM. Una angiografía coronaria descartó obstrucciones, y un ventriculograma reveló la característica imagen de "jarrón japonés" (la forma del corazón con STT), confirmando el diagnóstico. La paciente se recuperó favorablemente con manejo intensivo. El STT es crucial de considerar en mujeres posmenopáusicas con síntomas de infarto. Conclusión: El diagnóstico oportuno permite un tratamiento conservador y una recuperación completa de la función ventricular.

Takotsubo Syndrome (TTS), or broken heart syndrome, is a stress-induced transient cardiomyopathy, described in Japan in the 1990s. It presents with symptoms that mimic an acute myocardial infarction (AMI) and ST segment elevation, but without the presence of obstructive coronary artery disease. Case presentation: This is an 84-year-old woman who, after orthopedic surgery, suffered severe bradycardia, altered consciousness, and electrocardiographic changes suggestive of AMI. A coronary angiography ruled out obstructions, and a ventriculogram revealed the characteristic "Japanese vase" image (the shape of the heart with TTS), confirming the diagnosis. The patient recovered favorably with intensive management. STT is crucial to consider in postmenopausal women with heart attack symptoms. Conclusion: Timely diagnosis allows conservative treatment and complete recovery of ventricular function.

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Sendoya Alvarez, M. R. ., Saavedra Rodriguez, D. ., & Ortega Martinez, R. A. . (2026). Síndrome de Takotsubo: abordaje integral de un caso femenino en el Hospital Obrero N° 2, Cochabamba. Revista Vive, 9(25), 308–316. https://doi.org/10.33996/revistavive.v9i25.474
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Jennings R. Early phase of myocardial ischemic injury and infarction. Am J Cardiol. 1969;24(6):753-765. https://doi.org/10.1016/0002-9149(69)90464-0

Templin C, Ghadri J, Diekmann J, Napp L, Bataiosu D, Jaguszewski M, et al. Clinical features and outcomes of takotsubo (stress) cardiomyopathy. N Engl J Med. 2015;373(10):929-938. https://doi.org/10.1056/NEJMoa1406761

Ghadri J, Wittstein I, Prasad A, Sharkey S, Dote K, Akashi Y, et al. International expert consensus document on Takotsubo syndrome (part I): clinical characteristics, diagnostic criteria, and pathophysiology. Eur Heart J. 2018;39(22):2032-2046. https://doi.org/10.1093/eurheartj/ehy076

Pelliccia F, Kaski J, Crea F, Camici P. Pathophysiology of Takotsubo syndrome. Circulation. 2017;135(24):2426-2441. https://doi.org/10.1161/CIRCULATIONAHA.116.027121

Redfors B, Vedad R, Angerås O, Råmunddal T, Petursson P, Haraldsson I, et al. Mortality in takotsubo syndrome is similar to mortality in myocardial infarction—a report from the SWEDEHEART registry. Int J Cardiol. 2015;185:282-289. https://doi.org/10.1016/j.ijcard.2015.03.162

Wittstein I, Thiemann D, Lima J, Baughman K, Schulman S, Gerstenblith G, et al. Neurohumoral features of myocardial stunning due to sudden emotional stress. N Engl J Med. 2005;352(6):539-548. https://doi.org/10.1056/NEJMoa043046

Singh T, Khan H, Gamble D, Scally C, Newby D, Dawson D. Takotsubo syndrome: pathophysiology, emerging concepts, and clinical implications. Circulation. 2022;145(13):1002-1019. https://doi.org/10.1161/CIRCULATIONAHA.121.055854

Kato K, Lyon A, Ghadri J, Templin C. Takotsubo syndrome: aetiology, presentation and treatment. Heart. 2017;103(18):1461-1469. https://doi.org/10.1136/heartjnl-2016-309783

Ferreira V, Schulz J, Holmvang G, Kramer C, Carbone I, Sechtem U, et al. Cardiovascular magnetic resonance in nonischemic myocardial inflammation: expert recommendations. J Am Coll Cardiol. 2018;72(24):3158-3176. https://doi.org/10.1016/j.jacc.2018.09.072

Pillitteri M, Brogi E, Piagnani C, Bozzetti G, Forfori F. Perioperative management of Takotsubo cardiomyopathy: an overview. J Anesth Analg Crit Care. 2024;4(1):45. https://doi.org/10.1186/s44158-024-00178-y

Sharkey S, Windenburg D, Lesser J, Maron M, Hauser R, Lesser J, et al. Natural history and expansive clinical profile of stress (tako-tsubo) cardiomyopathy. J Am Coll Cardiol. 2010;55(4):333-341. https://doi.org/10.1016/j.jacc.2009.08.057

Ghadri J, Wittstein I, Prasad A, Sharkey S, Dote K, Akashi Y, et al. International expert consensus document on Takotsubo syndrome (part II): diagnostic workup, outcome, and management. Eur Heart J. 2018;39(22):2047-2062. https://doi.org/10.1093/eurheartj/ehy077

Rawish E, Stiermaier T, Santoro F, Brunetti N, Eitel I. Current knowledge and future challenges in Takotsubo syndrome: part 1—pathophysiology and diagnosis. J Clin Med. 2021;10(3):479. https://doi.org/10.3390/jcm10030479

Goto K, Nikolsky E, Lansky A, Dangas G, Witzenbichler B, Parise H, et al. Impact of smoking on outcomes of patients with ST-segment elevation myocardial infarction (from the HORIZONS-AMI Trial). Am J Cardiol. 2011;108(10):1387-1394. https://doi.org/10.1016/j.amjcard.2011.06.063

Naranjo S, Múnera A, Gaviria M, Gutiérrez D, Vásquez E, Duque M. Características clínicas, demográficas y epidemiológicas de una cohorte de pacientes con síndrome de Takotsubo entre 2011 y 2016 en Medellín, Colombia. Medicas UIS. 2021;34(1):27-33. https://doi.org/10.18273/revmed.v34n1-2021003

Zazueta V, González J, Ornelas J, Félix J. Características clínicas del síndrome de takotsubo: una serie de casos. Arch Cardiol Mex. 2023;93(2):203-211. https://doi.org/10.18273/revmed.v34n1-2021003

Lyon A, Bossone E, Schneider B, Sechtem U, Citro R, Underwood S, et al. Current state of knowledge on Takotsubo syndrome: a Position Statement from the Taskforce on Takotsubo Syndrome of the Heart Failure Association of the European Society of Cardiology. Eur J Heart Fail. 2016;18(1):8-27. https://doi.org/10.1002/ejhf.424

Pelliccia F, Pasceri V, Patti G, Tanzilli G, Speciale G, Gaudio C, et al. Long-term prognosis and outcome predictors in takotsubo syndrome: a systematic review and meta-regression study. JACC Heart Fail. 2019;7(2):143-154. https://doi.org/10.1016/j.jchf.2018.10.009